DNA Binding Site

Accessions: 2uzk_E (3D-footprint 20231221), 3l2c_C (3D-footprint 20231221)
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Length: 13
Sequence: GTTGTTTACATAG
Type: Heterodimer
Binding TFs: 2uzk_A (Fork head domain)
3l2c_A (Fork head domain)
Binding Motifs: 2uzk_A tGtTTA
3l2c_A GTAAACA
Publications: Tsai K. L., Sun Y. J., Huang C. Y., Yang J. Y., Hung M. C., Hsiao C. D. Crystal structure of the human FOXO3a-DBD/DNA complex suggests the effects of post-translational modification.. Nucleic Acids Res. 35:6984-6994 (2007). [Pubmed]

Boura E, Rezabkova L, Brynda J, Obsilova V, Obsil T. Structure of the human FOXO4-DBD-DNA complex at 1.9 Å resolution reveals new details of FOXO binding to the DNA. Acta crystallographica. Section D, Biological crystallography 66:1351-7 (2010). [Pubmed]

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