Transcription Factor
| Accessions: | UP00288A (UniPROBE 20160601) |
| Names: | Putative 128.2 kDa transcriptional regulatory protein in PTM1-IXR1 intergenic region, Rgt1, YKL038W, YKL251 |
| Organisms: | Saccharomyces cerevisiae |
| Libraries: | UniPROBE 20160601 1 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
| Uniprot: | P32862 |
| Description: | Glucose-responsive transcription factor that regulates expression of several glucose transporter (HXT) genes in response to glucose; binds to promoters and acts both as a transcriptional activator ... |
| Length: | 135 |
| Pfam Domains: | 44-84 Fungal Zn(2)-Cys(6) binuclear cluster domain |
| Sequence: (in bold interface residues) | 1 NELNTVSTNSSDSTKNGGTSNSPDDMDSAAAASHAIKKRTKASRACDQCRKKKIKCDYKD 60 61 EKGVCSNCQRNGDRCSFDRVPLKRGPSKGYTRSTSHPRTNEIQDHNNSRSYNTFDNSNNT 120 121 LNNNTGNSGDNGINS |
| Interface Residues: | 39, 40, 50, 52, 53, 54, 55, 70, 71 |
| 3D-footprint Homologues: | 1f5e_P, 1pyi_A, 3coq_A, 1d66_B, 6gys_C, 7uik_T |
| Binding Motifs: | UP00288A_1 hwcykyCGGAwaAAyttkmr |
| Binding Sites: | ATAATCCG ATATTCCG ATCTTCCG ATGATCCG ATGTTCCG ATTAATCC ATTATCCG ATTCTCCG ATTGTTCC ATTTTCCG CCGGAAGA CGGAAAAA CGGAACAA CGGAAGAA CGGAATAA CGGAGAAA CGGATAAA CGGATCAA CGGATTAA GGAAAAAC |
| Publications: | *Zhu C, *Byers K, *McCord RP, Shi Z, Berger MF, Newburger D, Saulrieta K, Smith Z, Shah M, Radhakrishnan M, Philippakis AA, Hu Y, De Masi F, Pacek M, Rolfs A , Murthy TVS, LaBaer J, Bulyk ML. High-Resolution DNA Binding Specificity Analysis of Yeast Transcription Factors. Genome Research. Epub January 21, 2009, doi:10.1101/gr.090233.108 (*co-1st authors). [Pubmed] |
| Related annotations: | PaperBLAST |
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