Transcription Factor
| Accessions: | UP00304A (UniPROBE 20160601) |
| Names: | Pre-rRNA-processing protein SRD1, Srd1, Suppressor of rRNA-processing defect protein 1, YCR018C, YCR18C |
| Organisms: | Saccharomyces cerevisiae |
| Libraries: | UniPROBE 20160601 1 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
| Uniprot: | P09007 |
| Description: | Protein involved in the processing of pre-rRNA to mature rRNA; contains a C2/C2 zinc finger motif; srd1 mutation suppresses defects caused by the rrp1-1 mutation |
| Length: | 104 |
| Pfam Domains: | 51-83 GATA zinc finger |
| Sequence: (in bold interface residues) | 1 QEANNLEGYHSCAQGTSRSASITKKYSKKTTSRPKREKRQTILPNGEIKECSKCKDTWTI 60 61 QWRSGPDQNRELCSPCGLAYGKRLKKENEKKRQAADKRIDRNNP |
| Interface Residues: | 60, 61, 63, 74, 78, 79 |
| 3D-footprint Homologues: | 1gat_A, 3dfx_B, 4gat_A |
| Binding Motifs: | UP00304A_1 swmdygRGATCTACamrcws |
| Binding Sites: | AAGATCTA AGAACTAC AGATCTAA AGATCTAC AGATCTAT AGATCTCA AGATCTCC AGATCTCG AGATCTGC CAGATCTA CGGAGATA CGTAGATC GAGATCTA GAGATCTC GATCTACA GGAACTAC GGATCTAC TAGATCCA TAGATCTA TCTTGGCA |
| Publications: | *Zhu C, *Byers K, *McCord RP, Shi Z, Berger MF, Newburger D, Saulrieta K, Smith Z, Shah M, Radhakrishnan M, Philippakis AA, Hu Y, De Masi F, Pacek M, Rolfs A , Murthy TVS, LaBaer J, Bulyk ML. High-Resolution DNA Binding Specificity Analysis of Yeast Transcription Factors. Genome Research. Epub January 21, 2009, doi:10.1101/gr.090233.108 (*co-1st authors). [Pubmed] |
| Related annotations: | PaperBLAST |
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