DNA Binding Site

Accessions: 3g73_D (3D-footprint 20231221), 6o3t_D (3D-footprint 20231221)
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Length: 19
Sequence: CGGGCTGTTTATAAACAAT
Type: Heterodimer
Binding TFs: 3g73_A (Fork head domain)
3g73_B (Fork head domain)
6o3t_B (Fork head domain)
Binding Motifs: 3g73_A TAAaCa
3g73_AB TgtTTATAAACA
6o3t_AB GTTTATAAACA
6o3t_B TAAaC
Publications: Littler D.R, Alvarez-Fernández M, Stein A, Hibbert R.G, Heidebrecht T, Aloy P, Medema R.H, Perrakis A. Structure of the FoxM1 DNA-recognition domain bound to a promoter sequence. Nucleic acids research 38:4527-38 (2010). [Pubmed]

Li S, Pradhan L, Ashur S, Joshi A, Nam HJ. Crystal Structure of FOXC2 in Complex with DNA Target. ACS Omega 4:10906-10914 (2019). [Pubmed]

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.