DNA Binding Motif

Accessions: 6o3t_AB (3D-footprint 20231221)
Names: Forkhead box protein C2
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Structural basis of FOXC2 and DNA interactions
Length: 11
Consensus: GTTTATAAACA
Weblogo:
PSSM: P0 A C G T
01 0 0 96 0 G
02 0 0 0 96 T
03 0 0 0 96 T
04 0 0 0 96 T
05 96 0 0 0 A
06 8 0 8 80 T
07 72 8 8 8 A
08 96 0 0 0 A
09 72 8 8 8 A
10 0 96 0 0 C
11 72 8 8 8 A
Type: Heterodimer
Binding TFs: 6o3t_A (Fork head domain)
6o3t_B (Fork head domain)
Binding Sites: 6o3t_C
6o3t_D
Publications: Li S, Pradhan L, Ashur S, Joshi A, Nam HJ. Crystal Structure of FOXC2 in Complex with DNA Target. ACS Omega 4:10906-10914 (2019). [Pubmed]

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