Transcription Factor

Accessions: 3g73_B (3D-footprint 20231221)
Names: Forkhead box protein M1, Forkhead-related protein FKHL16, FOXM1_HUMAN, Hepatocyte nuclear factor 3 forkhead homolog 11, HFH-11, HNF-3/fork-head homolog 11, M-phase phosphoprotein 2, MPM-2 reactive phosphoprotein 2, Transcription factor Trident, Winged-helix factor from INS-1 cells
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: Q08050
Length: 95
Pfam Domains: 3-86 Fork head domain
Sequence:
(in bold interface residues)
1 SERPPYSYMAMIQFAINSTERKRMTLKDIYTWIEDHFPYFKHIAKPGWKNSIRHNLSLHD 60
61 MFVRETSANGKVSFWTIHPSANRYLTLDQVFKPLD
Interface Residues: 47, 49, 50, 51, 53, 54, 55, 57, 58, 64, 71
3D-footprint Homologues: 7vox_H, 2hdc_A, 7yz7_A, 6el8_A, 7tdx_A, 3l2c_A, 7yzb_A, 6nce_A, 2uzk_A, 7vou_C, 2a07_J, 7yze_A, 7cby_C, 3co6_C, 6ako_C, 2c6y_A, 7yzg_A, 7tdw_A, 3g73_A, 3qrf_G
Binding Motifs: 3g73_AB TgtTTATAAACA
Binding Sites: 3g73_C
3g73_D
Publications: Littler D.R, Alvarez-Fernández M, Stein A, Hibbert R.G, Heidebrecht T, Aloy P, Medema R.H, Perrakis A. Structure of the FoxM1 DNA-recognition domain bound to a promoter sequence. Nucleic acids research 38:4527-38 (2010). [Pubmed]
Related annotations: PaperBLAST

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