DNA Binding Site
| Accessions: | CAAGGGCA (UniPROBE 20160601), MA0597.3.6 (JASPAR 2024) |
| Organisms: | Mus musculus, Homo sapiens |
| Libraries: | UniPROBE 20160601 1, JASPAR 2024 2 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Length: | 8 |
| Sequence: | CAAGGGCA |
| Type: | Heterodimer |
| Binding TFs: | UP00079A (Zinc finger, C4 type (two domains)) Q9NVV9 (THAP domain) Q9NVV9 |
| Binding Motifs: | UP00079A_1 kmkyCAAGGTCAtrykm UP00079A_2 vkbkAGGGGTCAarssm MA0597.3 gcAGGGCA |
| Publications: | Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed] Clouaire T, Roussigne M, Ecochard V, Mathe C, Amalric F, Girard J.P. The THAP domain of THAP1 is a large C2CH module with zinc-dependent sequence-specific DNA-binding activity. Proceedings of the National Academy of Sciences of the United States of America 102:6907-12 (2005). [Pubmed] |
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