DNA Binding Motif

						

			
Accessions: HOXB2_RFX5_1 (HumanTF2 1.0)

			
Names: HOXB2_RFX5
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 20
Consensus: symATTAscvcmyrGyAACs
Weblogo: 
PSSM: P0      A      C      G      T
01    295    529    588    245      s
02    199    553    147    565      y
03    452    666    135     86      m
04   1118     89    184     23      A
05      1      5      0   1118      T
06     75    304     21   1118      T
07   1118     23     23    148      A
08    262    354    348    153      s
09    148    484    278    207      c
10    306    305    356    150      v
11    152    585    219    162      c
12    361    333    228    195      m
13     97    332     87    601      y
14    622    219    496     46      r
15    203     46   1118     35      G
16    120   1118     44    434      y
17   1118      3     71     38      A
18   1118     20     17     11      A
19      4   1118      9     26      C
20    227    326    454    111      s
Type: Heterodimer
Binding TFs: HOXB2_TF1 (Homeobox domain)
RFX5_TF2 (RFX DNA-binding domain, Poxvirus D5 protein-like)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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