DNA Binding Motif

						

			
Accessions: FLI1_ETV7 (HumanTF2 1.0), UN0528.1 (JASPAR 2024)

			
Names: FLI1_ETV7, FLI1::ETV7
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1, JASPAR 2024 2
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX, HT-SELEX
Length: 18
Consensus: rsmGGAmGGAtdTCCgsb
Weblogo: 
PSSM: P0      A      C      G      T
01   1195    812    999    652      r
02    545   1776   1501    509      s
03   1188   2253    585    161      m
04     52      0   3644     32      G
05     57      8   3631     22      G
06   3646     49     64     24      A
07   1591   2986     21     17      m
08     32      0   3652      6      G
09      0     33   3653     28      G
10   3654     28     18      4      A
11    969    847     19   2473      t
12   1215     11   1195   1238      d
13     28      8      7   3641      T
14     18   3654      1      7      C
15      8   3628      0     61      C
16    126    603   2400   1039      g
17    437   1317   1846    753      s
18    616    939   1035   1069      b
Type: Heterodimer
Binding TFs: Q9Y603 (Ets-domain, Sterile alpha motif (SAM)/Pointed domain)
FLI1_TF2 (Ets-domain, Sterile alpha motif (SAM)/Pointed domain)
FLI1_Full (Ets-domain, Sterile alpha motif (SAM)/Pointed domain)
ETV7_TF1 / ETV7_TF2 (Ets-domain, Sterile alpha motif (SAM)/Pointed domain)
Q9Y603
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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