DNA Binding Motif

						

			
Accessions: ETV2_ONECUT2_2_3_4 (HumanTF2 1.0)

			
Names: ETV2_ONECUT2
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 20
Consensus: acCGGAWryrrrkATCGATy
Weblogo: 
PSSM: P0      A      C      G      T
01   2118    168    955    619      a
02    605   3073   1076    136      c
03    483   3073     25      1      C
04      3      8   3073     17      G
05      0      0   3073     12      G
06   3073     14      8      0      A
07   3073     90      1   1066      W
08    829    225   1981     38      r
09    318   1014    320   1421      y
10   1014    511   1083    464      r
11    890    670    964    549      r
12    887    690    785    711      r
13    650    472   1027    924      k
14   3073     39    744    190      A
15     59      5     11   3073      T
16     41   3073     46    849      C
17    407     24   3073     27      G
18   3073     17     15     79      A
19    270    791    104   3073      T
20    443    888    524   1218      y
Type: Heterodimer
Binding TFs: ONECUT2_TF2 (Homeobox domain, CUT domain)
ETV2_TF1 (Ets-domain)
ONECUT2_Full (Homeobox domain, CUT domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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