DNA Binding Motif

						

			
Accessions: FOXO1_ELF1_2 (HumanTF2 1.0), UN0535.1 (JASPAR 2024)

			
Names: FOXO1_ELF1, FOXO1::ELF1
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1, JASPAR 2024 2
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX, HT-SELEX
Length: 15
Consensus: kTGTTGCCGGAAgkk
Weblogo: 
PSSM: P0      A      C      G      T
01     92     68    164    116      k
02     27     25      0    440      T
03     86      7    440     13      G
04     16      6      0    440      T
05     42      0    127    440      T
06     22     10    440    156      G
07     94    311     21     14      C
08     42    440     31      6      C
09      2      2    440      0      G
10      0      7    440     13      G
11    440     20     20     21      A
12    440      0     15     56      A
13    110     37    331     23      g
14     59     87    112    183      k
15    107     67    155    112      k
Type: Heterodimer
Binding TFs: ELF1_TF2 (Ets-domain, Transcription factor protein N terminal)
FOXO1_TF1 / FOXO1_TF2 (Fork head domain)
Q12778 (Fork head domain)
Q12778
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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