DNA Binding Motif

						

			
Accessions: POU2F1_FOXO6_2_3 (HumanTF2 1.0)

			
Names: POU2F1_FOXO6
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 28
Consensus: gmATATkCAhrawwwhawrmmrtmAACA
Weblogo: 
PSSM: P0      A      C      G      T
01    123     67    550     71      g
02    442    232     26     38      m
03    673    111     32    130      A
04     76     60      5    673      T
05    673      1      8      0      A
06     28     17      8    673      T
07     32      1    339    334      k
08      5    673     13     62      C
09    472     32    109     60      A
10    179    188    125    182      h
11    198    127    246    102      r
12    316    101    117    139      a
13    230    129    103    211      w
14    170     90     75    339      w
15    217    167     87    202      w
16    174    180    103    216      h
17    304    145    117    107      a
18    211    145     90    228      w
19    244     80    234    115      r
20    207    241     58    168      m
21    215    202    143    113      m
22    255    114    419     27      r
23    194     77     49    479      t
24    438    236    119    105      m
25    673    111     14     15      A
26    673     24     10     18      A
27     30    673      7    130      C
28    673      5     39     91      A
Type: Heterodimer
Binding TFs: FOXO6_TF2 (Fork head domain)
POU2F1_TF1 (Homeobox domain, Pou domain - N-terminal to homeobox domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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