DNA Binding Motif

Accessions: ETV5_TCF3_1 (HumanTF2 1.0)
Names: ETV5_TCF3
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 17
Consensus: CAsGTGsrscGGAagkg
Weblogo:
PSSM: P0 A C G T
01 39 418 25 20 C
02 418 22 45 15 A
03 5 141 277 23 s
04 30 98 319 6 G
05 9 31 19 418 T
06 12 0 418 2 G
07 60 119 134 104 s
08 192 41 225 120 r
09 58 140 171 49 s
10 71 270 59 17 c
11 15 7 418 15 G
12 10 22 418 0 G
13 418 40 36 19 A
14 418 63 80 182 a
15 120 82 418 29 g
16 41 95 117 165 k
17 98 64 188 68 g
Type: Heterodimer
Binding TFs: ETV5_TF1 (Ets-domain)
TCF3_TF2 (Helix-loop-helix DNA-binding domain)
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

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