DNA Binding Motif

						

			
Accessions: ETV2_DLX3_2 (HumanTF2 1.0)

			
Names: ETV2_DLX3
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 19
Consensus: acCGGAAryrvsvyaATtr
Weblogo: 
PSSM: P0      A      C      G      T
01   1801    203    618    344      a
02    463   1892    527    125      c
03    436   2419      2     19      C
04      5      1   2419      2      G
05      1      0   2419      0      G
06   2419      0      0      0      A
07   2419     72     19    707      A
08   1007     76   1305     30      r
09    250    979    252    937      y
10    751    499    813    356      r
11    756    665    658    339      v
12    477    714    722    505      s
13    675    663    680    401      v
14    303    982    104   1437      y
15   2419    447    445    433      a
16   2419    342     97    349      A
17    148    148    166   2419      T
18    389    626    605   2419      t
19   2419    234   1428    648      r
Type: Heterodimer
Binding TFs: DLX3_TF2 (Homeobox domain)
DLX3_Crystal (Homeobox domain)
DLX3_Full (Homeobox domain, Homeobox protein distal-less-like N terminal )
ETV2_TF1 (Ets-domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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