DNA Binding Motif

Accessions: RFX3_BHLHA15 (HumanTF2 1.0)
Names: RFX3_BHLHA15
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 18
Consensus: TrGCaACgavCATATGkt
Weblogo:
PSSM: P0 A C G T
01 48 21 40 255 T
02 178 2 186 14 r
03 23 15 364 4 G
04 45 296 23 68 C
05 364 12 67 140 a
06 364 4 12 0 A
07 5 364 16 25 C
08 65 69 208 22 g
09 172 48 83 62 a
10 103 157 93 11 v
11 0 364 0 5 C
12 364 5 30 17 A
13 0 17 32 364 T
14 364 7 0 10 A
15 0 21 7 364 T
16 0 0 364 28 G
17 0 37 242 122 k
18 47 68 47 203 t
Type: Heterodimer
Binding TFs: BHLHA15_TF2 (Helix-loop-helix DNA-binding domain)
RFX3_TF1 (RFX DNA-binding domain)
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

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