DNA Binding Motif

						

			
Accessions: ETV2_FOXI1_2_3 (HumanTF2 1.0), UN0513.1 (JASPAR 2024)

			
Names: ETV2_FOXI1, ETV2::FOXI1
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1, JASPAR 2024 2
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX, HT-SELEX
Length: 17
Consensus: rcCGGAAryrtmmACAy
Weblogo: 
PSSM: P0      A      C      G      T
01    289     91    221     67      r
02     73    373    137     49      c
03    131    511     31     16      C
04     21     44    511      6      G
05      8     16    511     34      G
06    511     26     17      2      A
07    511     30     18    130      A
08    170     73    237     31      r
09     18    137     11    345      y
10    174     44    337     10      r
11    117     48     90    463      t
12    303    207     16     54      m
13    511    302     67     78      m
14    511     38     90    102      A
15     12    511     11     57      C
16    511     39     66     74      A
17    127    134     93    156      y
Type: Heterodimer
Binding TFs: FOXI1_TF2 (Fork head domain)
ETV2_TF1 (Ets-domain)
Q3KNT2 (Ets-domain)
Q3KNT2
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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