DNA Binding Motif

						

			
Accessions: HOXA3 (HumanTF2 1.0), UN0558.1 (JASPAR 2024)

			
Names: HOXA3
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1, JASPAR 2024 2
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: HT-SELEX; HT-SELEX generated reference PWM, HT-SELEX
Length: 10
Consensus: rsTMATTAas
Weblogo: 
PSSM: P0      A      C      G      T
01    757    476    887    420      r
02     93   1246   1294    138      s
03      0    502      0   2540      T
04   2540   1022     10      0      M
05   2540      0      0      0      A
06      0      0      0   2540      T
07      0      0    517   2540      T
08   2540      0    361      0      A
09    859    531    617    533      a
10    339    975    676    550      s
Type: Heterodimer
Binding TFs: O43365 (Homeobox domain, Domain of unknown function (DUF4074))
HOXA3_TF1 / HOXA3_TF2 (Homeobox domain)
O43365
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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