Transcription Factor

						

			
Accessions: O43365 (JASPAR 2024)

			
Names: Homeobox protein Hox-1E, Homeobox protein Hox-A3, HXA3_HUMAN
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Length: 443
Pfam Domains:   192-248 Homeobox domain
  376-441 Domain of unknown function (DUF4074)
Sequence: 
(in bold interface residues)		   1 MQKATYYDSSAIYGGYPYQAANGFAYNANQQPYPASAALGADGEYHRPACSLQSPSSAGG   60
  61 HPKAHELSEACLRTLSAPPSQPPSLGEPPLHPPPPQAAPPAPQPPQPAPQPPAPTPAAPP  120
 121 PPSSASPPQNASNNPTPANAAKSPLLNSPTVAKQIFPWMKESRQNTKQKTSSSSSGESCA  180
 181 GDKSPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQ  240
 241 NRRMKYKKDQKGKGMLTSSGGQSPSRSPVPPGAGGYLNSMHSLVNSVPYEPQSPPPFSKP  300
 301 PQGTYGLPPASYPASLPSCAPPPPPQKRYTAAGAGAGGTPDYDPHAHGLQGNGSYGTPHI  360
 361 QGSPVFVGGSYVEPMSNSGPALFGLTHLPHAASGAMDYGGAGPLGSGHHHGPGPGEPHPT  420
 421 YTDLTGHHPSQGRIQEAPKLTHL
Interface Residues: 155, 158, 159, 162, 183, 192, 193, 194, 195, 233, 234, 236, 237, 240, 241, 244, 245, 248
3D-footprint Homologues: 5zfz_A, 3a01_E, 1ig7_A, 2h1k_B, 1puf_A, 6a8r_A, 3cmy_A, 1fjl_B, 6m3d_C, 1jgg_B, 3lnq_A, 2lkx_A, 1nk2_P, 1zq3_P, 2ld5_A, 7q3o_C, 6es3_K, 5flv_I, 3l1p_A, 5zjt_E, 4j19_B, 7psx_B, 5hod_A, 2hdd_A, 1au7_A, 5jlw_D, 3rkq_B, 2r5y_A, 1puf_B, 4xrs_G, 2hos_A, 1b72_A, 4cyc_A, 1e3o_C, 1le8_A, 7xrc_C, 2xsd_C, 1o4x_A, 1du0_A, 4qtr_D, 3d1n_M
Binding Motifs: UN0558.1 rsTMATTAas
MA2119.1 sTMATTA
			
Publications: Jaeger SA, Chan ET, Berger MF, Stottmann R, Hughes TR, Bulyk ML. Conservation and regulatory associations of a wide affinity range of mouse transcription factor binding sites. Genomics 95:185-95 (2010). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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