DNA Binding Motif

Accessions: FOXO1_ELF1_1 (HumanTF2 1.0)
Names: FOXO1_ELF1
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 14
Consensus: cagAAAACCGAAwm
Weblogo:
PSSM: P0 A C G T
01 471 931 362 311 c
02 1111 430 194 340 a
03 571 215 2074 426 g
04 2074 63 28 145 A
05 2074 13 3 20 A
06 2074 67 19 8 A
07 2074 9 0 0 A
08 0 2074 7 0 C
09 18 2074 30 0 C
10 19 0 2074 3 G
11 2074 67 0 17 A
12 2074 4 30 152 A
13 735 456 159 724 w
14 1003 1071 130 463 m
Type: Heterodimer
Binding TFs: ELF1_TF2 (Ets-domain, Transcription factor protein N terminal)
FOXO1_TF1 / FOXO1_TF2 (Fork head domain)
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

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