DNA Binding Motif

						

			
Accessions: 1hlz_AB (3D-footprint 20231221)

			
Names: ORPHAN NUCLEAR RECEPTOR NR1D1
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: CRYSTAL STRUCTURE OF THE ORPHAN NUCLEAR RECEPTOR REV-ERB(ALPHA) DNA-BINDING DOMAIN BOUND TO ITS COGNATE RESPONSE ELEMENT
Length: 17
Consensus: TGACCTnnTGACCAnnT
Weblogo: 
PSSM: P0      A      C      G      T
01      5      4      4     83      T
02      0      0     96      0      G
03     66      8     14      8      A
04      0     96      0      0      C
05      0     96      0      0      C
06      8      5      8     75      T
07     24     24     24     24      n
08     24     24     24     24      n
09      1      0      4     91      T
10      0      0     96      0      G
11     83      5      4      4      A
12      0     96      0      0      C
13      0     96      0      0      C
14     70     10      8      8      A
15     24     24     24     24      n
16     24     24     24     24      n
17      0      5      4     87      T
Type: Heterodimer
Binding TFs: 1hlz_A (Zinc finger, C4 type (two domains))
1hlz_B (Zinc finger, C4 type (two domains))
Binding Sites: 1hlz_D
1hlz_C
			
Publications: Sierk M.L, Zhao Q, Rastinejad F. DNA deformability as a recognition feature in the reverb response element. Biochemistry 40:12833-43 (2001). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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