DNA Binding Motif

Accessions: UP00384A_1 (UniPROBE 20160601)
Names: HLH-2
Organisms: Caenorhabditis elegans
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Length: 14
Consensus: wbraatataawvht
Weblogo:
PSSM: P0 A C G T
01 0.35 0.18 0.22 0.25 w
02 0.14 0.25 0.27 0.34 b
03 0.30 0.24 0.29 0.16 r
04 0.65 0.08 0.08 0.18 a
05 0.63 0.13 0.06 0.18 a
06 0.18 0.19 0.08 0.55 t
07 0.62 0.13 0.08 0.17 a
08 0.18 0.17 0.10 0.55 t
09 0.54 0.06 0.15 0.24 a
10 0.53 0.16 0.19 0.12 a
11 0.31 0.16 0.09 0.44 w
12 0.31 0.25 0.30 0.14 v
13 0.36 0.26 0.12 0.25 h
14 0.13 0.24 0.07 0.55 t
Binding TFs: UP00384A (Helix-loop-helix DNA-binding domain)
Binding Sites: ACACGCGC
ACACGCGT
ACATGCGC
ACATGCGT
ACCACGCG
ACGCATGG
ACGCGTGG
CACGCATG
CACGCGTA
CACGCGTG
CACGTGTC
CATGCGTA
CCACGCGC
CCATGCGC
CGCATGGC
CGCATGTC
CGCGTGGC
CGCGTGTC
CGTGTGTC
GCGTGTCC
Publications: Grove C.A, De Masi F, Barrasa M.I, Newburger D.E, Alkema M.J, Bulyk M.L, Walhout A.J. A multiparameter network reveals extensive divergence between C. elegans bHLH transcription factors. Cell 138:314-27 (2009). [Pubmed]

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