DNA Binding Motif

						

			
Accessions: TEAD4_HES7_2_3 (HumanTF2 1.0)

			
Names: TEAD4_HES7
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 17
Consensus: rcATwCCrvCrCGyGys
Weblogo: 
PSSM: P0      A      C      G      T
01    293     32    309     18      r
02    216    603     61     11      c
03    603     12     54     10      A
04     20     11      0    603      T
05    494     17     80    603      w
06     33    603     63     14      C
07     36    603     16     96      C
08    245     86    163    109      r
09    202    172    209     20      v
10     40    603      0      1      C
11    393     69    210     91      r
12      1    603      1     62      C
13     63      9    603      4      G
14     40    193     10    410      y
15     12     18    603     46      G
16    104    337    135    265      y
17     98    241    165     99      s
Type: Heterodimer
Binding TFs: HES7_TF2 (Helix-loop-helix DNA-binding domain)
TEAD4_TF1 (TEA/ATTS domain family)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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