DNA Binding Motif

						

			
Accessions: FLI1_DLX2_2 (HumanTF2 1.0)

			
Names: FLI1_DLX2
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 19
Consensus: rvmGGAArtsvsyaaTtar
Weblogo: 
PSSM: P0      A      C      G      T
01    205    104    158     97      r
02    162    211    152     40      v
03    184    363     52      0      m
04      4      0    363      2      G
05      0      8    363      1      G
06    363      0     18      7      A
07    363     14      0    100      A
08    156     74    101     31      r
09     67     64     46    186      t
10     83     94    114     72      s
11    111     98    107     47      v
12     56    102    127     78      s
13     65    207      5    156      y
14    363    171     89     86      a
15    363    131     23     73      a
16      0     34     28    363      T
17     39     67     70    363      t
18    363     10    107     86      a
19    110     66    109     78      r
Type: Heterodimer
Binding TFs: DLX2_TF2 (Homeobox domain, Homeobox protein distal-less-like N terminal )
FLI1_TF2 (Ets-domain, Sterile alpha motif (SAM)/Pointed domain)
FLI1_Full (Ets-domain, Sterile alpha motif (SAM)/Pointed domain)
DLX2_Full (Homeobox domain, Homeobox protein distal-less-like N terminal )
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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