DNA Binding Motif

						

			
Accessions: TEAD4_HES7_2_3_4 (HumanTF2 1.0)

			
Names: TEAD4_HES7
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 20
Consensus: rmATwCCacmsvCaCGyGys
Weblogo: 
PSSM: P0      A      C      G      T
01    220     32    213     11      r
02    174    433     60     15      m
03    433      9     65      6      A
04     12      6      0    433      T
05    351     24     92    433      w
06     39    433     11     27      C
07     43    433     18    118      C
08    160     75     93    106      a
09     98    139     99     98      c
10    111    142     99     81      m
11     99    120    132     82      s
12    144    130    110     50      v
13     14    433      6      9      C
14    308     26    125     69      a
15      3    433      6     35      C
16     46     14    433      4      G
17     34    184     13    250      y
18     20     10    433     51      G
19    109    266    115    168      y
20     65    133    140     96      s
Type: Heterodimer
Binding TFs: HES7_TF2 (Helix-loop-helix DNA-binding domain)
TEAD4_TF1 (TEA/ATTS domain family)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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