DNA Binding Motif

Accessions: GCM1_HOXA2 (HumanTF2 1.0)
Names: GCM1_HOXA2
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 15
Consensus: rTrsGGGygTrATkr
Weblogo:
PSSM: P0 A C G T
01 477 61 295 31 r
02 0 0 10 772 T
03 258 32 514 5 r
04 119 477 296 171 s
05 95 19 772 48 G
06 4 4 772 10 G
07 15 17 772 8 G
08 54 414 69 236 y
09 114 172 330 156 g
10 156 72 115 772 T
11 772 0 320 61 r
12 772 0 31 0 A
13 27 81 222 772 T
14 37 255 365 408 k
15 433 156 340 112 r
Type: Heterodimer
Binding TFs: GCM1_TF1 (GCM motif protein)
HOXA2_TF2 (Homeobox domain)
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

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