DNA Binding Motif

						

			
Accessions: HOXB2_PAX1_2 (HumanTF2 1.0)

			
Names: HOXB2_PAX1
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 21
Consensus: rymaTtaGTCACGCwTsrcTG
Weblogo: 
PSSM: P0      A      C      G      T
01    191    135    286    135      r
02    109    224    184    230      y
03    248    384    177    113      m
04    623    135    203    121      a
05      1     40     23    744      T
06     24    283    117    714      t
07    634    271    147     58      a
08      1      0    749      2      G
09     15      1      4    740      T
10      1    744      0     35      C
11    745      5      1      3      A
12      0    743      0     55      C
13      0      0    747      0      G
14      0    738    100      0      C
15    408     36     22    303      w
16      8    100      0    732      T
17      0    346    401      0      s
18    488      7    257      0      r
19    115    283    178    171      c
20      0    106      7    749      T
21    169      3    688    107      G
Type: Heterodimer
Binding TFs: HOXB2_TF1 (Homeobox domain)
PAX1_TF2 ('Paired box' domain, Homeodomain-like domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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