DNA Binding Motif

						

			
Accessions: GCM1_FOXI1_1 (HumanTF2 1.0), UN0545.1 (JASPAR 2024)

			
Names: GCM1_FOXI1, GCM1::FOXI1
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1, JASPAR 2024 2
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX, HT-SELEX
Length: 14
Consensus: rTGTTGATrcGGGy
Weblogo: 
PSSM: P0      A      C      G      T
01    661    195    843    279      r
02    214    152    146   1978      T
03    338     21   1978     20      G
04    172     81    334   1978      T
05     69    116    236   1978      T
06     31      0   1978    246      G
07   1978    111    185    115      A
08     36     82     56   1978      T
09    977      0   1001      0      r
10    179   1183    482    134      c
11    203      0   1978     54      G
12     24      0   1978      0      G
13     91      8   1978     26      G
14    211    776    243    748      y
Type: Heterodimer
Binding TFs: FOXI1_TF2 (Fork head domain)
GCM1_TF1 (GCM motif protein)
Q9NP62 (GCM motif protein)
Q9NP62
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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