DNA Binding Motif

						

			
Accessions: HOXB2_SOX15_2_3_4_5 (HumanTF2 1.0)

			
Names: HOXB2_SOX15
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 19
Consensus: stmATyasmvmvraCAATg
Weblogo: 
PSSM: P0      A      C      G      T
01     24     67     63     12      s
02     49     59     41    107      t
03    107     59     28     26      m
04    166     18     25     14      A
05     24      9      9    166      T
06     33     96     36    166      y
07    166     14     68     42      a
08     39     51     48     27      s
09     46     59     31     30      m
10     50     58     43     15      v
11     71     55     18     22      m
12     54     46     46     20      v
13     78     15     44     29      r
14    166     28     24     41      a
15     30    166      0     30      C
16    166      0     18     13      A
17    166      5     21     33      A
18     52     20      0    166      T
19     54     33    112     22      g
Type: Heterodimer
Binding TFs: HOXB2_TF1 (Homeobox domain)
SOX15_TF2 (HMG (high mobility group) box, Domain of unknown function (DUF1898))
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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