DNA Binding Motif

Accessions: ELK1_TBX21_2 (HumanTF2 1.0)
Names: ELK1_TBX21
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 14
Consensus: tcrCACCGGAAgyr
Weblogo:
PSSM: P0 A C G T
01 1211 2321 1261 6882 t
02 1626 3464 1240 552 c
03 4705 410 2177 1305 r
04 716 6882 1084 462 C
05 6882 121 1871 164 A
06 446 6882 519 50 C
07 1397 6882 19 0 C
08 0 0 6882 12 G
09 0 2 6882 45 G
10 6882 4 110 8 A
11 6882 103 89 1950 A
12 1668 1735 6882 398 g
13 641 2166 1384 2691 y
14 1883 1345 2301 1354 r
Type: Heterodimer
Binding TFs: ELK1_TF2 (Ets-domain)
ELK1_Full (Ets-domain)
TBX21_TF2 (T-box)
ELK1_TF1 (Ets-domain)
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

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