DNA Binding Motif

						

			
Accessions: E2F3_FOXO6_2 (HumanTF2 1.0)

			
Names: E2F3_FOXO6
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 18
Consensus: gaaTGACACcGCGCCCac
Weblogo: 
PSSM: P0      A      C      G      T
01    365    356    636    184      g
02    971    428    245    160      a
03   1288    432    137    142      a
04    200    260    109   1364      T
05    135     65   1477     30      G
06   1493     98     28     36      A
07      8   1523      0    197      C
08   1537     23      7      0      A
09     25   1534      0      7      C
10     86    988    187    281      c
11     75     68   1536     53      G
12      5   1534     22      0      C
13    114     50   1506     79      G
14    303   1481     31     93      C
15    100   1495     20     42      C
16    229   1261     57    115      C
17    871    321     66    284      a
18    290    763    224    264      c
Type: Heterodimer
Binding TFs: FOXO6_TF2 (Fork head domain)
E2F3_TF1 (E2F/DP family winged-helix DNA-binding domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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