DNA Binding Motif

Accessions: ELK1_TBX21_2_3 (HumanTF2 1.0)
Names: ELK1_TBX21
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 29
Consensus: agGTGykAaawwwwwtTmaCACMGGAart
Weblogo:
PSSM: P0 A C G T
01 2038 259 407 390 a
02 483 276 828 452 g
03 99 325 2038 164 G
04 36 343 30 2038 T
05 106 5 2038 42 G
06 307 534 166 1031 y
07 180 273 970 614 k
08 2038 74 307 121 A
09 941 302 332 462 a
10 630 467 440 500 a
11 657 309 326 745 w
12 701 354 303 680 w
13 690 390 245 713 w
14 728 300 364 645 w
15 608 362 379 689 w
16 498 266 360 913 t
17 155 341 65 1477 T
18 774 623 327 314 m
19 1033 115 469 420 a
20 111 2038 10 47 C
21 1567 4 440 27 A
22 155 1592 240 51 C
23 562 1475 63 12 M
24 72 26 2038 38 G
25 28 33 2038 29 G
26 2038 45 76 175 A
27 1491 148 114 547 a
28 588 382 778 289 r
29 415 503 292 828 t
Type: Heterodimer
Binding TFs: ELK1_TF2 (Ets-domain)
ELK1_Full (Ets-domain)
TBX21_TF2 (T-box)
ELK1_TF1 (Ets-domain)
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

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