DNA Binding Motif

						

			
Accessions: ETV5_DLX2 (HumanTF2 1.0)

			
Names: ETV5_DLX2
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 18
Consensus: rsCGGAwrtvrsymATTA
Weblogo: 
PSSM: P0      A      C      G      T
01    734    216    463    268      r
02    285    686    511    142      s
03    347   1197    126     37      C
04     17      0   1197      0      G
05      7      1   1197      4      G
06   1197      0      2      0      A
07   1197    173     26    679      w
08    334    252    549     62      r
09    228    275    184    511      t
10    315    304    365    214      v
11    397    250    416    134      r
12    236    335    486    140      s
13     51    767     22    431      y
14   1197    664    502    242      m
15   1197    252     84     98      A
16      0      0     19   1197      T
17     32    151     45   1197      T
18   1197     23    155    239      A
Type: Heterodimer
Binding TFs: DLX2_TF2 (Homeobox domain, Homeobox protein distal-less-like N terminal )
ETV5_TF1 (Ets-domain)
DLX2_Full (Homeobox domain, Homeobox protein distal-less-like N terminal )
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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