DNA Binding Motif

						

			
Accessions: 5hlh_AC (3D-footprint 20231221)

			
Names: MarR family transcriptional regulator
Organisms: Staphylococcus epidermidis, strain ATCC 35984 / RP62A
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal structure of the overoxidized AbfR bound to DNA
Length: 20
Consensus: CGATTnAGnnnnCTnAATCG
Weblogo: 
PSSM: P0      A      C      G      T
01      0     96      0      0      C
02      0      0     96      0      G
03     86      4      3      3      A
04      0      3      0     93      T
05      3      3      3     87      T
06     24     24     24     24      n
07     86      4      3      3      A
08      6      5     76      9      G
09     24     24     24     24      n
10     24     24     24     24      n
11     24     24     24     24      n
12     24     24     24     24      n
13      3     76      6     11      C
14      3      3      1     89      T
15     24     24     24     24      n
16     83      6      4      3      A
17     93      0      3      0      A
18      3      3      4     86      T
19      0     96      0      0      C
20      0      0     96      0      G
Type: Heterodimer
Binding TFs: 5hlh_A (MarR family, HxlR-like helix-turn-helix, Sugar-specific transcriptional regulator TrmB, Transcriptional regulator PadR-like family, FeoC like transcriptional regulator, MarR family, Winged helix DNA-binding domain)
5hlh_C (MarR family, HxlR-like helix-turn-helix, Sugar-specific transcriptional regulator TrmB, Transcriptional regulator PadR-like family, FeoC like transcriptional regulator, MarR family, Winged helix DNA-binding domain)
Binding Sites: 5hlh_I
5hlh_J
			
Publications: Liu G, Liu X, Xu H, Liu X, Zhou H, Huang Z, Gan J, Chen H, Lan L, Yang CG. Structural Insights into the Redox-Sensing Mechanism of MarR-Type Regulator AbfR. J Am Chem Soc 139:1598-1608 (2017). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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