Transcription Factor

Accessions: 5hlh_C (3D-footprint 20231221)
Names: MarR family transcriptional regulator, Q5HKZ1_STAEQ
Organisms: Staphylococcus epidermidis, strain ATCC 35984 / RP62A
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: Q5HKZ1
Length: 132
Pfam Domains: 27-84 Sugar-specific transcriptional regulator TrmB
31-89 MarR family
32-98 Winged helix DNA-binding domain
32-89 MarR family
37-105 HxlR-like helix-turn-helix
45-86 FeoC like transcriptional regulator
55-101 Transcriptional regulator PadR-like family
Sequence:
(in bold interface residues)
1 EQMRLANQLFSAYNVSRLFAQFYEKKLKQFGITYSQYLVLLTLWEENPQTLNSIGRHLDL 60
61 SSNTLTPMLKRLEQSGWVKRERQQSDKRQLIITLTDNGQQQQEAVFEAISSCLYDETKYV 120
121 FEELEQTLKHLI
Interface Residues: 52, 61, 62, 63, 64, 66, 67, 68, 70, 71, 88
3D-footprint Homologues: 7el3_B, 6c2s_C, 3q5f_A, 6jbx_A, 4lln_I, 7dvv_A, 5yi2_J, 5h3r_A, 1z9c_A, 4fx4_B, 5hlg_E, 3zpl_B, 5f7q_C, 4aik_A, 5hso_A
Binding Motifs: 5hlh_AC CGATTnAGnnnnCTnAATCG
Binding Sites: 5hlh_I
5hlh_J
Publications: Liu G, Liu X, Xu H, Liu X, Zhou H, Huang Z, Gan J, Chen H, Lan L, Yang CG. Structural Insights into the Redox-Sensing Mechanism of MarR-Type Regulator AbfR. J Am Chem Soc 139:1598-1608 (2017). [Pubmed]
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.