Transcription Factor

Accessions: 5hlh_A (3D-footprint 20231221)
Names: MarR family transcriptional regulator, Q5HKZ1_STAEQ
Organisms: Staphylococcus epidermidis, strain ATCC 35984 / RP62A
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: Q5HKZ1
Length: 134
Pfam Domains: 28-85 Sugar-specific transcriptional regulator TrmB
32-90 MarR family
33-99 Winged helix DNA-binding domain
33-90 MarR family
38-106 HxlR-like helix-turn-helix
46-87 FeoC like transcriptional regulator
56-102 Transcriptional regulator PadR-like family
Sequence:
(in bold interface residues)
1 QEQMRLANQLFSAYNVSRLFAQFYEKKLKQFGITYSQYLVLLTLWEENPQTLNSIGRHLD 60
61 LSSNTLTPMLKRLEQSGWVKRERQQSDKRQLIITLTDNGQQQQEAVFEAISSCYDETKYV 120
121 FEELEQTLKHLIEK
Interface Residues: 53, 62, 63, 64, 65, 67, 68, 69, 71, 72, 89
3D-footprint Homologues: 7el3_B, 7dvv_A, 5yi2_J, 5h3r_A, 1z9c_A, 6c2s_C, 3q5f_A, 6jbx_A, 4lln_I, 3zpl_B, 5f7q_C, 4aik_A, 4fx4_B, 5hlg_E, 5hso_A
Binding Motifs: 5hlh_AC CGATTnAGnnnnCTnAATCG
Publications: Liu G, Liu X, Xu H, Liu X, Zhou H, Huang Z, Gan J, Chen H, Lan L, Yang CG. Structural Insights into the Redox-Sensing Mechanism of MarR-Type Regulator AbfR. J Am Chem Soc 139:1598-1608 (2017). [Pubmed]
Related annotations: PaperBLAST

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