DNA Binding Motif

						

			
Accessions: ETV2_FOXI1_2_3_4_5 (HumanTF2 1.0), UN0515.1 (JASPAR 2024)

			
Names: ETV2_FOXI1, ETV2::FOXI1
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1, JASPAR 2024 2
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX, HT-SELEX
Length: 14
Consensus: TGTtkmCGGAWGtg
Weblogo: 
PSSM: P0      A      C      G      T
01    138    288    193   1943      T
02    432     50   1943     96      G
03    160    220    189   1943      T
04    245    140    678   1943      t
05    143     13    981    962      k
06   1358    584    100     12      m
07      0   1943     31     10      C
08      1     16   1943     38      G
09      0     37   1943     35      G
10   1943     75     67    105      A
11   1438      7      0    505      W
12    371     59   1571     29      G
13    144    579    245   1943      t
14    363    321    870    388      g
Type: Heterodimer
Binding TFs: FOXI1_TF2 (Fork head domain)
ETV2_TF1 (Ets-domain)
Q3KNT2 (Ets-domain)
Q3KNT2
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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