DNA Binding Motif

Accessions: 1dh3_AC (3D-footprint 20231221)
Names: TRANSCRIPTION FACTOR CREB
Organisms: Mus musculus
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: CRYSTAL STRUCTURE OF A CREB BZIP-CRE COMPLEX REVEALS THE BASIS FOR CREB FAIMLY SELECTIVE DIMERIZATION AND DNA BINDING
Length: 8
Consensus: TgnCgTCA
Weblogo:
PSSM: P0 A C G T
01 0 0 0 96 T
02 16 13 54 13 g
03 24 24 24 24 n
04 0 96 0 0 C
05 13 13 54 16 g
06 0 0 0 96 T
07 0 96 0 0 C
08 96 0 0 0 A
Binding TFs: 1dh3_A / 1dh3_C (bZIP transcription factor, Basic region leucine zipper)
Binding Sites: 1dh3_B / 1dh3_D
Publications: Schumacher M.A, Goodman R.H, Brennan R.G. The structure of a CREB bZIP.somatostatin CRE complex reveals the basis for selective dimerization and divalent cation-enhanced DNA binding. The Journal of biological chemistry 275:35242-7 (2000). [Pubmed]

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