Transcription Factor

Accessions: 1dh3_A (3D-footprint 20231221), 1dh3_C (3D-footprint 20231221)
Names: cAMP-responsive element-binding protein 1, CREB-1, CREB1_MOUSE, Cyclic AMP-responsive element-binding protein 1, TRANSCRIPTION FACTOR CREB
Organisms: Mus musculus
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: Q01147
Length: 55
Pfam Domains: 1-53 bZIP transcription factor
3-49 Basic region leucine zipper
Sequence:
(in bold interface residues)
1 KREVRLMKNREAARESRRKKKEYVKSLENRVAVLENQNKTLIEELKALKDLYSHK
Interface Residues: 5, 9, 10, 12, 13, 16, 17
3D-footprint Homologues: 4zpr_B, 5vpe_D, 1dh3_C, 5t01_B
Binding Motifs: 1dh3_AC TgnCgTCA
1dh3_C CGnCA
Binding Sites: 1dh3_B / 1dh3_D
Publications: Schumacher M.A, Goodman R.H, Brennan R.G. The structure of a CREB bZIP.somatostatin CRE complex reveals the basis for selective dimerization and divalent cation-enhanced DNA binding. The Journal of biological chemistry 275:35242-7 (2000). [Pubmed]
Related annotations: PaperBLAST

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