DNA Binding Motif

						

			
Accessions: GCM1_PITX1_2_3 (HumanTF2 1.0)

			
Names: GCM1_PITX1
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 18
Consensus: GGaTTAwggsGrTGCGGG
Weblogo: 
PSSM: P0      A      C      G      T
01     21      0    143      4      G
02      4      7    143      8      G
03    143     36     19     21      a
04      0      0     17    143      T
05     18     20     26    143      T
06    143      0     11     10      A
07     45     19     29     49      w
08     20     26     74     22      g
09     27     32     56     27      g
10     11     38     82     11      s
11      0     31    106      6      G
12     65      8     40     30      r
13     26      7      7    143      T
14     28      0    143      6      G
15     15    143     14     26      C
16     25      4    143     15      G
17      0      4    143      2      G
18      4      4    143      0      G
Type: Heterodimer
Binding TFs: GCM1_TF1 (GCM motif protein)
PITX1_TF1 / PITX1_TF2 (Homeobox domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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