DNA Binding Motif

Accessions: 5krb_BG (3D-footprint 20231221)
Names: Nuclear receptor subfamily 6 group A member 1
Organisms: Mus musculus
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: GCNF DNA Binding Domain - Oct4 DR0 Complex
Length: 11
Consensus: GGTCAaGGnCA
Weblogo:
PSSM: P0 A C G T
01 0 0 96 0 G
02 0 0 96 0 G
03 0 0 0 96 T
04 0 96 0 0 C
05 80 0 8 8 A
06 64 8 8 16 a
07 0 0 96 0 G
08 0 0 96 0 G
09 24 24 24 24 n
10 0 80 8 8 C
11 72 8 8 8 A
Type: Heterodimer
Binding TFs: 5krb_B (Zinc finger, C4 type (two domains))
5krb_G (Zinc finger, C4 type (two domains))
Binding Sites: 5krb_A
5krb_E
Publications: Weikum ER, Tuntland ML, Murphy MN, Ortlund EA. A Structural Investigation into Oct4 Regulation by Orphan Nuclear Receptors, Germ Cell Nuclear Factor (GCNF), and Liver Receptor Homolog-1 (LRH-1). J Mol Biol : (2016). [Pubmed]

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