DNA Binding Motif

						

			
Accessions: TEAD4_HES7_2 (HumanTF2 1.0)

			
Names: TEAD4_HES7
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 20
Consensus: ggwATGyrkgrsrCrCGyGb
Weblogo: 
PSSM: P0      A      C      G      T
01    161     72    518     78      g
02     79    122    518     76      g
03    317     65     23    201      w
04    518      3     40     19      A
05      8     60      9    518      T
06     25     43    518    150      G
07     40    281     42    237      y
08    149    110    169     90      r
09     92    122    170    134      k
10    129    125    145    119      g
11    144    116    130    128      r
12     76    131    255     55      s
13    189     73    198     57      r
14     89    518     34     44      C
15    294     18    224     26      r
16      7    518     23    146      C
17     68      1    518      3      G
18     27    209     38    309      y
19     14     16    518     52      G
20     83    298    202    220      b
Type: Heterodimer
Binding TFs: HES7_TF2 (Helix-loop-helix DNA-binding domain)
TEAD4_TF1 (TEA/ATTS domain family)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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