DNA Binding Motif

						

			
Accessions: ERF_ETV7 (HumanTF2 1.0), UN0506.1 (JASPAR 2024)

			
Names: ERF_ETV7, ERF::ETV7
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1, JASPAR 2024 2
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX, HT-SELEX
Length: 18
Consensus: rsmGGAmGGAykTCCkss
Weblogo: 
PSSM: P0      A      C      G      T
01    565    408    436    248      r
02    428    893    764    313      s
03    677    981    451    102      m
04     55      0   1657      5      G
05      2      3   1657      0      G
06   1657     16      9     19      A
07   1105   1657      9      0      m
08      2      3   1657      0      G
09      0      0   1657      5      G
10   1657      6      5      2      A
11    387    534      0   1124      y
12    386     40    618    613      k
13     11     11      3   1657      T
14      4   1657      0      2      C
15      1   1657      2     71      C
16    206    456    941    716      k
17    409    823    835    554      s
18    337    465    495    360      s
Type: Heterodimer
Binding TFs: Q9Y603 (Ets-domain, Sterile alpha motif (SAM)/Pointed domain)
ERF_TF1 (Ets-domain)
ETV7_TF1 / ETV7_TF2 (Ets-domain, Sterile alpha motif (SAM)/Pointed domain)
Q9Y603
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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