DNA Binding Motif

						

			
Accessions: ETV2_HOXB13_1 (HumanTF2 1.0)

			
Names: ETV2_HOXB13
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 16
Consensus: rvCGGAwrymrTwAam
Weblogo: 
PSSM: P0      A      C      G      T
01   1061    355   1071    455      r
02   2198   2942   2088    942      v
03   1006   2942    206     19      C
04      0      7   2942      0      G
05      0      6   2942      0      G
06   2942      5      7     70      A
07   2942    726     17   2086      w
08   1362    231   2942      0      r
09     77   1360     84   2942      y
10   1766   1987    808    955      m
11    839     27   2104    158      r
12      0    239      2   2942      T
13   2942    347    641   2446      w
14   2942     29     64    513      A
15   2942   1087    583    737      a
16    819    834    712    577      m
Type: Heterodimer
Binding TFs: HOXB13_TF1 / HOXB13_TF2 (Homeobox domain)
ETV2_TF1 (Ets-domain)
HOXB13_Full (Homeobox domain, Hox protein A13 N terminal)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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