DNA Binding Motif

Accessions: POU2F1_SOX15_1 (HumanTF2 1.0)
Names: POU2F1_SOX15
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 13
Consensus: wtGmATaACAAwr
Weblogo:
PSSM: P0 A C G T
01 886 228 208 944 w
02 357 332 282 1830 t
03 173 24 1830 22 G
04 942 887 37 89 m
05 1830 87 38 108 A
06 0 0 5 1830 T
07 1830 239 581 214 a
08 1830 10 4 284 A
09 38 1830 282 353 C
10 1830 29 0 32 A
11 1830 5 4 26 A
12 1053 149 75 1830 w
13 1154 229 676 129 r
Type: Heterodimer
Binding TFs: POU2F1_TF1 (Homeobox domain, Pou domain - N-terminal to homeobox domain)
SOX15_TF2 (HMG (high mobility group) box, Domain of unknown function (DUF1898))
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

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