DNA Binding Motif

						

			
Accessions: ETV2_TEF_1 (HumanTF2 1.0), UN0522.1 (JASPAR 2024)

			
Names: ETV2_TEF, ETV2::TEF
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1, JASPAR 2024 2
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX, HT-SELEX
Length: 17
Consensus: rCCGGAwrTTACGTAAy
Weblogo: 
PSSM: P0      A      C      G      T
01   1387    247   1038    543      r
02    231   1950    476     17      C
03    233   2426    131     52      C
04      0      8   2426    176      G
05      5     17   2426      0      G
06   2426     13      0      6      A
07   1588    156     12    837      w
08    968    126   1324      8      r
09      0      6     23   2426      T
10     48     28    162   2426      T
11   1953      6    472      0      A
12     14   2426     16    314      C
13    706     33   2426     12      G
14      0    406     17   2020      T
15   2426    249     18     17      A
16   2426     28     23     23      A
17     55   1110    347    913      y
Type: Heterodimer
Binding TFs: TEF_TF1 / TEF_TF2 (bZIP transcription factor, Basic region leucine zipper)
ETV2_TF1 (Ets-domain)
Q3KNT2 (Ets-domain)
Q3KNT2
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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