DNA Binding Motif

Accessions: E2F3_FOXI1 (HumanTF2 1.0)
Names: E2F3_FOXI1
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 15
Consensus: tGACACCGCGCCCaC
Weblogo:
PSSM: P0 A C G T
01 400 411 400 1040 t
02 449 155 1563 82 G
03 1953 297 133 101 A
04 155 2250 80 217 C
05 2250 121 6 55 A
06 45 2250 57 13 C
07 53 2250 186 124 C
08 101 154 2250 68 G
09 17 2250 0 51 C
10 209 233 2250 83 G
11 39 2250 49 54 C
12 88 2250 0 92 C
13 608 2250 32 75 C
14 1615 635 126 296 a
15 355 1558 184 154 C
Type: Heterodimer
Binding TFs: FOXI1_TF2 (Fork head domain)
E2F3_TF1 (E2F/DP family winged-helix DNA-binding domain)
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

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