DNA Binding Motif

Accessions: UP00386A_1 (UniPROBE 20160601)
Names: HLH-25
Organisms: Caenorhabditis elegans
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Length: 16
Consensus: rrgrCGCGTGTCCywk
Weblogo:
PSSM: P0 A C G T
01 0.38 0.18 0.26 0.17 r
02 0.32 0.19 0.32 0.17 r
03 0.14 0.17 0.48 0.21 g
04 0.39 0.05 0.53 0.02 r
05 0.01 0.98 0.01 0.01 C
06 0.21 0.01 0.75 0.02 G
07 0 0.89 0 0.11 C
08 0.15 0 0.84 0 G
09 0 0.01 0 0.99 T
10 0 0 0.99 0 G
11 0.01 0 0.10 0.89 T
12 0.01 0.94 0.01 0.05 C
13 0.01 0.85 0.01 0.13 C
14 0.11 0.52 0.08 0.28 y
15 0.31 0.23 0.17 0.29 w
16 0.23 0.15 0.32 0.31 k
Binding TFs: UP00386A (Helix-loop-helix DNA-binding domain)
Binding Sites: ACACGCGC
ACACGCGT
ACATGCGC
ACATGCGT
ACCACGCG
ACGCATGG
ACGCGTGG
CACGCATG
CACGCGTA
CACGCGTG
CACGTGTC
CATGCGTA
CCACGCGC
CCATGCGC
CGCATGGC
CGCATGTC
CGCGTGGC
CGCGTGTC
CGTGTGTC
GCGTGTCC
Publications: Grove C.A, De Masi F, Barrasa M.I, Newburger D.E, Alkema M.J, Bulyk M.L, Walhout A.J. A multiparameter network reveals extensive divergence between C. elegans bHLH transcription factors. Cell 138:314-27 (2009). [Pubmed]

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