DNA Binding Motif

Accessions: ERF_HES7_1 (HumanTF2 1.0)
Names: ERF_HES7
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 21
Consensus: rCCGGAAgygcGrCACGyGsc
Weblogo:
PSSM: P0 A C G T
01 97 41 58 20 r
02 41 217 36 13 C
03 47 217 3 0 C
04 0 2 217 2 G
05 0 0 217 5 G
06 217 1 2 6 A
07 217 5 9 59 A
08 52 28 129 7 g
09 21 56 26 114 y
10 51 35 84 47 g
11 46 84 42 45 c
12 5 33 173 5 G
13 85 16 90 25 r
14 4 217 1 4 C
15 217 15 44 19 A
16 7 217 15 0 C
17 23 7 217 45 G
18 5 79 13 137 y
19 12 18 217 23 G
20 18 85 66 47 s
21 44 114 28 32 c
Type: Heterodimer
Binding TFs: HES7_TF2 (Helix-loop-helix DNA-binding domain)
ERF_TF1 (Ets-domain)
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

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