DNA Binding Motif

						

			
Accessions: HOXB2_ELF1_2_3 (HumanTF2 1.0)

			
Names: HOXB2_ELF1
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 22
Consensus: gymATyAgsgraksmGGAAGtr
Weblogo: 
PSSM: P0      A      C      G      T
01    571    655   1318    366      g
02    578   1251    788   1660      y
03   1409   1502    677    193      m
04   2911    283    715    119      A
05     37     26     17   2911      T
06    347   1184     72   2911      y
07   2911     46    176    291      A
08    630    688   1271    323      g
09    372    857   1122    561      s
10    590    676    996    649      g
11   1084    402    744    682      r
12   1404    197    601    709      a
13    684    626    755    846      k
14    645   1070   1050    146      s
15    860   1959     97      0      m
16      7      0   2911     11      G
17     22     15   2911      0      G
18   2911      3      5     72      A
19   2911     24     20    132      A
20    431    377   2911     19      G
21    321    624    432   1534      t
22    907    428   1151    426      r
Type: Heterodimer
Binding TFs: ELF1_TF2 (Ets-domain, Transcription factor protein N terminal)
HOXB2_TF1 (Homeobox domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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