DNA Binding Motif

						

			
Accessions: ETV5_HOXA2_2 (HumanTF2 1.0)

			
Names: ETV5_HOXA2
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 23
Consensus: rscGGwAATgrstdwdsymaTtA
Weblogo: 
PSSM: P0      A      C      G      T
01    653    132    719    272      r
02    274    812    594    145      s
03    424   1343    148    137      c
04     25     72   1501     22      G
05     46    109   1493     47      G
06   1005     24      0    499      w
07   1415     23    117    113      A
08   1488     32    117     16      A
09     84    201     58   1439      T
10    113    225   1005    429      g
11    383    252    654    219      r
12    291    404    543    269      s
13    302    371    349    486      t
14    401    257    409    441      d
15    469    334    309    396      w
16    413    279    425    391      d
17    256    414    525    313      s
18    200    444    363    501      y
19    503    845    424    212      m
20   1340    182    368    105      a
21     20     37     20   1487      T
22    139    431     97   1339      t
23   1411     47    195    259      A
Type: Heterodimer
Binding TFs: ETV5_TF1 (Ets-domain)
HOXA2_TF2 (Homeobox domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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